
Eflornithine hydrochloride Monohydrate
CAS No. 96020-91-6
Eflornithine hydrochloride Monohydrate( DFMO | Eflornithine )
Catalog No. M16851 CAS No. 96020-91-6
Eflornithine hydrochloride, hydrate (DFMO; MDL-71782) is a drug found to be effective in the treatment of facial hirsutism.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
50MG | 27 | In Stock |
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100MG | 38 | In Stock |
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200MG | 52 | In Stock |
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500MG | 112 | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameEflornithine hydrochloride Monohydrate
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NoteResearch use only, not for human use.
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Brief DescriptionEflornithine hydrochloride, hydrate (DFMO; MDL-71782) is a drug found to be effective in the treatment of facial hirsutism.
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DescriptionEflornithine hydrochloride, hydrate (DFMO; MDL-71782) is a drug found to be effective in the treatment of facial hirsutism.(In Vivo):Eflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.
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In Vitro——
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In VivoEflornithine is the only new molecule registered for the treatment of human African trypanosomiasis over the last 50 years. It is the drug used mainly as a back-up for melarsoprol refractory Trypanosoma brucei gambiense cases. In subjects with excessive, unwanted facial hair, eflornithine 15% cream is superior to placebo in reducing hair growth. After 24 weeks' treatment, 58% of eflornithine and 34% of placebo subjects have at least some improvement in facial hirsutism. The hair growth inhibitory activity of eflornithine is significantly enhanced when the eflornithine cream is applied onto a mouse skin area pretreated with microneedles. Treatment of coarctation hypertensive rats with eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension.
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SynonymsDFMO | Eflornithine
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number96020-91-6
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Formula Weight236.64
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Molecular FormulaC6H15ClF2N2O3
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Purity>98% (HPLC)
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SolubilitySoluble in DMSO
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SMILESO.Cl.NCCCC(N)(C(F)F)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Mohammed A, et al. Y Prev Res (Phila). 2014 Dec;7(12):1198-209.
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